An Efficient Secure Anonymous Proxy Signature Scheme

Proxy signature schemes can be used in many business applications such as when the original signer is not present to sign important documents. Any proxy signature scheme has to meet the identifiability, undeniability, verifiability and unforgeability security requirements. In some conditions, it may be necessary to protect the proxy signer’s privacy from outsiders or third parties. Recently, several studies about proxy signature schemes have been conducted but only Yu et al.’ anonymous proxy signature scheme proposed in 2009 attempting to protect the proxy signer’s privacy from outsiders. They claimed their scheme can make the proxy signer anonymous. However, based on our research, we determined that this was not the case and the proxy signer’s privacy was not anonymous. Hence, in this paper, we propose a new anonymous proxy signature scheme that truly makes the proxy signer anonymous while making it more secure and efficient when compared with Yu et al.’s scheme in 2009. Our proxy signature scheme consists of two constructions. First, we mainly use random numbers and bilinear pairings to attain the anonymous property in our proxy. Secondly, we increase the security, integrity, and efficiency of our proxy through modifications

Evaluation on the Pharmacological Effect of Traditional Chinese Medicine SiJunZiTang on Stress-Induced Peptic Ulcers

Purpose. To explore the effects of SiJunZiTang (SJZT) on central neurotransmitters and the inhibition of HCl hypersecretion, along with the role of the vagus nerve. From this, the effects of SJZT and its constituent ingredients on inhibiting stress-induced peptic ulcers will be determined. Methods. Methods used to determine SJZT's effectiveness included (1) measuring the antipeptic ulcer effects of varying combinations of the constituents of SJZT; (2) evaluations of monoamine (MA) level in the brain; and (3) measuring the effects of longer-term SJZT treatment. Results. Comparing the control and experimental groups where the rats’ vagus nerves were not cut after taking SJZT orally (500 mg/kg and 1000 mg/kg), the volume of enterogastric juice, free HCl and total acidity all reduce dose-dependently. The group administered SJZT at 1000 mg/kg showed significant reductions (P<0.05). For the experimental groups where the vagus nerves were cut, a comparison with the control group suggests that the group receiving SJZT (500 mg/kg) orally for 21 days demonstrated a cure rate of 34.53%. Conclusion. The results display a correlation between the therapeutic effects of SJZT on stress-induced peptic ulcers and central neurotransmitter levels. Further to this, SJZT can inhibit the hypersecretion of HCl in the stomach, thus inhibiting stress-induced peptic ulcers

Perceptions, Behavioral Expectations, and Implementation Timing for Response Actions in a Hurricane Emergency

This study examined the perceived attributes, behavioral expectations, and expected implementation timing of 11 organizational emergency response actions for hurricane emergencies. The perceived attributes of the hurricane response actions were characterized by two hazard-related attributes (effectiveness for person protection and property protection) and five resource-related attributes (financial costs, required knowledge/skill, required equipment, required time/effort, and required cooperation). A total of 155 introductory psychology students responded to a hypothetical scenario involving an approaching Category 4 hurricane. The data collected in this study explain previous findings of untimely protective action decision making. Specifically, these data reveal distinctly different patterns for the expected implementation of preparatory actions and evacuation recommendations. Participants used the hazard-related and resource-related attributes to differentiate among the response actions and the expected timing of implementation. Moreover, participants’ behavioral expectations and expected implementation timing for the response actions were most strongly correlated with those actions’ effectiveness for person protection. Finally, participants reported evacuation implementation times that were consistent with a phased evacuation strategy in which risk areas are evacuated in order of their proximity to the coast. However, the late initiation of evacuation in risk areas closest to the coast could lead to very late evacuation of risk areas farther inland

Well-differentiated gall bladder hepatoid carcinoma producing alpha-fetoprotein: a case report

<p>Abstract</p> <p>Introduction</p> <p>Gall bladder carcinoma is rare, and metastatic gall bladder carcinoma from hepatocellular carcinoma has been reported in only a few patients.</p> <p>Case presentation</p> <p>We present a 73-year-old man with a history of hepatitis B virus-related liver cirrhosis and hepatocellular carcinoma. He received transcatheter arterial chemoembolization, and was diagnosed to have an alpha-fetoprotein producing gall bladder tumor with intraluminal growth. Open cholecystectomy was performed. Pathologic examination of the lesion revealed a well-differentiated hepatoid carcinoma. The lesion was thought most likely to be a metastatic lesion from previous hepatocellular carcinoma. His alpha-fetoprotein level dropped to normal levels five months after the surgery.</p> <p>Conclusion</p> <p>This unusual intraluminal growing tumor proved to be a well-differentiated hepatoid carcinoma, most likely a metastatic lesion from previous hepatocellular carcinoma. This case reminds clinicians that in looking for likely hepatocellular carcinoma recurrence, when no detectable hepatic lesion can account for an elevated alpha-fetoprotein level, the gall bladder should be included in the search for the site of metastasis.</p

Benzodiazepines Associated With Acute Respiratory Failure in Patients With Obstructive Sleep Apnea

Aims: Obstructive sleep apnea (OSA) and insomnia commonly coexist; hypnotics are broadly prescribed for insomnia therapy. However, the safety of hypnotics use in OSA patients is unclear. We conducted a retrospective case-control study to investigate the risk of adverse respiratory events in hypnotics-using OSA patients.Methods: We obtained data from the Taiwan National Health Insurance Database from 1996 to 2013. The case group included 216 OSA patients with newly diagnosed adverse respiratory events, including pneumonia and acute respiratory failure. The control group included OSA patients without adverse respiratory events, which was randomly frequency-matched to the case group at a 1:1 ratio according to age, gender, and index year. Hypnotics exposure included benzodiazepines (BZD) and non-benzodiazepines (non-BZD). A recent user was defined as a patient who had taken hypnotics for 1–30 days, while a long-term user was one who had taken hypnotics for 31–365 days.Results: Multivariable adjusted analysis showed recent BZD use is an independent risk for adverse respiratory events (OR = 2.70; 95% CI = 1.15–6.33; P &lt; 0.001). Subgroup analysis showed both recent and long-term BZD use increased the risk of acute respiratory failure compared to never BZD use (OR = 28.6; 95% CI = 5.24–156; P &lt; 0.001, OR = 10.1; 95% CI = 1.51–67.7; P &lt; 0.05, respectively). Neither BZD nor non-BZD use increased the risk of pneumonia in OSA patients.Conclusion: BZD use might increase the risk of acute respiratory failure in OSA patients